Abstract:
Sepsis and septic shock are one of the most common causes of death in patients in intensive care units. In modern literary sources there is no generally accepted definition of sepsis, which causes some difficulties in assessing this severe pathological condition. In a study published by the American Center for disease control."..to this day, the frequency of septicemia vozrosla 73,6 up to 100 000 больных of 175.9". According to American and European surveys."..the incidence of sepsis ranges from 2 to 11% of all hospitalized patients or patients in intensive care units". The first barrier to immune protection from pathogens is the complement system, acute phase proteins, cytokines and monocytes, macrophages, neutrophils and natural killer cells."..if this defense fails, the inflammatory response gets out of control and can lead to either irrepressible microbial reproduction or damage to body tissues, vascular collapse, and multi-organ failure."
