Clinical Features and Lab Values of Patients with Chronic Hepatitis after Covid-19

Abstract

In scientific studies on the study of COVID-19, the researchers have reported that 14-53% of the cases showed signs of mild to moderate liver damage: increased levels of aminotransferases, hypoproteinemia, and an increase in prothrombin time. The severe course of the disease was associated with signs of liver damage. Exacerbation of pre-existing chronic liver disease leads to a more severe course of COVID-19 infection. The direct action of the SARS-CoV-2 virus can directly affect liver cells, as evidenced by the detection of increased expression of ACE-2 receptors in cholangiocytes [1,2]. Patients with advanced stages of chronic diffuse liver disease have a higher risk of infection due to immune disorders associated with the presence of cirrhosis [3]. The aim of the study was to study the clinical, functional and metabolic characteristics of patients with chronic hepatitis who had Covid-19.