Abstract:
In scientific studies on the study of COVID-19, the researchers have reported that 14-53% of the cases showed
signs of mild to moderate liver damage: increased levels of aminotransferases, hypoproteinemia, and an increase in
prothrombin time. The severe course of the disease was associated with signs of liver damage. Exacerbation of pre-existing
chronic liver disease leads to a more severe course of COVID-19 infection. The direct action of the SARS-CoV-2 virus can
directly affect liver cells, as evidenced by the detection of increased expression of ACE-2 receptors in cholangiocytes [1,2].
Patients with advanced stages of chronic diffuse liver disease have a higher risk of infection due to immune disorders
associated with the presence of cirrhosis [3]. The aim of the study was to study the clinical, functional and metabolic
characteristics of patients with chronic hepatitis who had Covid-19.