Evaluation of genotypic allelic variants of IL6 and IL10 genes in the pathogenesis of gastric ulcer according to SNP-PCR detection

Abstract

Peptic ulcer of the stomach is still considered one of the etiologically multifactorial diseases, rich in pathogenetic nature of topical problems. Currently, the analysis of the distribution of polymorphic alleles and genotypically unfavorable variants of pro- inflammatory and anti-inflammatory cytokines in patients with gastroduodenal pathology is considered one of the most advanced areas of modern gastroenterology. According to the literature data, interleukin proteins, endogenous polypeptide mediators of intercellular interaction, IL6 and IL10, 1].