Prediction of COVID-19 manipulation by selective ACE inhibitory compounds of Potentilla reptant root: In silico study and ADMET profile

Yuan Xu, Mahmood Al-Mualm,  Ermias Mergia Terefe, Maksuda Ilyasovna Shamsutdinova, Maria Jade Catalan Opulencia, Fahad Alsaikhan, Abduladheem Turki Jalil, Ali Thaeer Hammid, Ayesheh Enayati, Hassan Mirzaei i, Vahid Khori i , Ali Jabbari i , Aref Salehi i, Alireza Soltani, Abdullah Mohamed

dc.contributor.author	Yuan Xu, Mahmood Al-Mualm, Ermias Mergia Terefe, Maksuda Ilyasovna Shamsutdinova, Maria Jade Catalan Opulencia, Fahad Alsaikhan, Abduladheem Turki Jalil, Ali Thaeer Hammid, Ayesheh Enayati, Hassan Mirzaei i, Vahid Khori i , Ali Jabbari i , Aref Salehi i, Alireza Soltani, Abdullah Mohamed
dc.date.accessioned	2022-12-16T06:49:02Z
dc.date.available	2022-12-16T06:49:02Z
dc.date.issued	2022
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/5336
dc.description.abstract	In the novel SARS-CoV-2 (COVID-19) as a global emergency event, the main reason of the cardiac injury from COVID-19 is angiotensin-converting enzyme 2 (ACE2) targeting in SARS- CoV-2 infection. The inhibition of ACE2 induces an increase in the angiotensin II (Ang II) and the angiotensin II receptor type 1 (AT1R) leading to impaired cardiac function or cardiac inflammatory	en_US
dc.language.iso	en_US	en_US
dc.publisher	Arabian Journal of Chemistry	en_US
dc.relation.ispartofseries	УДК;
dc.subject	COVID-19; Potentilla reptans; Angiotensin II;	en_US
dc.title	Prediction of COVID-19 manipulation by selective ACE inhibitory compounds of Potentilla reptant root: In silico study and ADMET profile	en_US
dc.type	Article	en_US