Experimental substantiation of the use of hypoxia-inducible factor (hif-1α) for the development of toxic hepatitis.

Sayfutdinova Z.A., Karimov Kh.Y.,Saidov.A.B

dc.contributor.author	Sayfutdinova Z.A., Karimov Kh.Y.,Saidov.A.B
dc.date.accessioned	2023-01-27T16:19:24Z
dc.date.available	2023-01-27T16:19:24Z
dc.date.issued	2021-01
dc.identifier.isbn	978-1-64945-242-9
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/6136
dc.description.abstract	This article provides an experimental rationale for the use of hypoxia-inducible factor (HIF-1α) for the development and course of toxic hepatitis based on heliotrin intoxication. Acute heliotrin intoxication was reproduced by a single subcutaneous administration of a sublethal dose of heliotrin to rats, prepared at the rate of 40 mg per 100 g of body weight. During the reproduction of experimental toxic hepatitis by the introduction of heliotrin, it was found that the HIF-1 content was on average 0.101667 ± 0.0022 ng / L. In blood plasma, the mean HIF-1 values were 0.2136 ± 0.0066 ng / L.	en_US
dc.language.iso	en	en_US
dc.publisher	Cutting edge-science,Shawnee,USA Conference Proceedings	en_US
dc.relation.ispartofseries	83pp;
dc.subject	hypoxia-inducible factor; heliotrin intoxication; experimental toxic hepatitis; aryl hydrocarbon receptor transolator	en_US
dc.title	Experimental substantiation of the use of hypoxia-inducible factor (hif-1α) for the development of toxic hepatitis.	en_US
dc.type	Thesis	en_US