Abstract:
Separate repeated action of pesticides in small doses can affect the genetic apparatus of both somatic and generative cells. However, with repeated combined action of pesticides in generative and somatic cells, there was no increase (sensitization) or decrease in the cytogenetic effect when using one drug with another. The cytogenetic effect of dalapon was studied in somatic (bone marrow) cells using tests for accounting, chromosome aberrations in metaphase in bone marrow cells. There are few data on the genetic effect of pesticides obtained on an animal object, especially on mammals, taking into account chromosome aberrations.