Abstract:
Purpose of the study: Assessment of oral microbiota in oncological diseases of
the oral cavity. Materials and methods: 20 patients with cancer in the oral
cavity were selected from the surgical department No. 6 of the Republican
Oncology Center: reconstructive, plastic surgery, head and neck tumors and
onco-ophthalmology department. Their saliva was examined in the
Bacteriological Laboratory of the TTA multidisciplinary clinic, and blood agar,
VSA, endo, and Saburo media were used in the examination of patients.
Antibiotic sensitivity was checked by disk diffusion method. Analysis and
discussion of results. 75% of patients are men, 25% are women. In 15
patients, 10 men and 5 women, bacteria close to the normal microflora of the
oral cavity, and pathogenic bacteria in 5 men were detected. Conclusion: Oral
microbiota composition and functionality are now considered to be associated
with mutational changes in oral cancer. During the examination of patients
with oncological diseases in the oral cavity, the bacteria detected in them are
similar to normal bacteria, but they cannot be called completely normal(Staf.
аureus 25%). The reason for this is explained by the fact that patients receive
light therapy and take various powerful drugs. Such factors affect the normal
microflora.
