Abstract:
Recent studies have completely changed the idea of the course of malignant diseases, in particular breast cancer (BC). For practical oncology, the addition to the conventional TNM clinical and morphological classification with the concept of four molecular biological subtypes of breast cancer has become important. Genetic classification included a variety of disease options: from luminal A, luminal B to three times negative. A completely new round of research on the biological activity of breast cancer has changed not only the clinical understanding of the process of active metastasis or its long-term latent existence in the body, but also the tactics of treatment based on the results of relapse-free and overall survival. Luminal A and three times negative variants of breast cancer are polar
in many ways.
