Abstract:
In recent decades, the role of a chronic inflammatory process in
the development of cardiovascular complications in patients with coronary artery
disease and diabetes has been actively discussed. Target. study of markers of the
vascular inflammatory process in patients with coronary artery disease in
combination with type 2 diabetes. Identify a set of laboratory parameters that can
become predictors of cardiovascular complications. Materials and methods. We
examined 69 patients aged 60.3±9.8 years with coronary artery disease, stable
exertional angina. Patients are divided into 2 groups. Group 1 - patients with IHD
(n=30), Group 2 - IHD with type 2 diabetes (n=39). Results. The study of
laboratory parameters of blood serum was carried out against the background of
standard therapy before and after 12±2.4 months of observation. Initially, in the
2nd group of patients, a significant excess of the level of atherogenic parameters of
the lipid profile (total cholesterol, VLDL, TG) and markers of inflammation
(highly sensitive C-reactive protein, fibrinorgen ) was revealed compared to the 1st
group.
