Abstract:
Systemic vasculitis (SV) is a systemic autoimmune disease of unknown etiology,
pathogenetically associated with immunoregulatory disorders that cause hyperproduction of a wide
range of organ-nonspecific autoantibodies to various components of the nucleus and immune
complexes, causing immuno-inflammatory damage to blood vessels and dysfunction of internal organs
[1, 6,8,9,10].
Vasculitis is characterized by multivariable manifestations, course and prognosis, exacerbations and
remissions. Potential targets for immune aggression can be a variety of antigens of the nervous tissue
[1, 2, 7]. Studies conducted in recent years have proven the commonality and interconnection of the
nervous and immune systems, and the results of experimental developments have confirmed the
similarity between their structures and functions, which contributed to the development of a new
direction - neuroimmunology
